D364-0234 Screening compound: 3-benzyl-5-[5-(1-ethyl-1H-indol-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,2,3,4-tetrahydropyrimidine-2,4-dione

D364-0234 Screening compound: 3-benzyl-5-[5-(1-ethyl-1H-indol-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,2,3,4-tetrahydropyrimidine-2,4-dione
D364-0234 Screening compound: 3-benzyl-5-[5-(1-ethyl-1H-indol-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D364-0234
3-benzyl-5-[5-(1-ethyl-1H-indol-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D364-0234

Molecular Formula

C24H23N5O3 (C24 H23 N5 O3)

Compound Name

3-benzyl-5-[5-(1-ethyl-1H-indol-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

3-benzyl-5-[5-(1-ethyl-1H-indol-3-yl)-45-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1234-tetrahydropyrimidine-24-dione

SMILES

CCn1c(cccc2)c2c(C(C2)NN=C2C(C(N(Cc2ccccc2)C(N2)=O)=O)=C2O)c1

InChI

InChI=1S/C24H23N5O3/c1-2-28-14-17(16-10-6-7-11-20(16)28)18-12-19(27-26-18)21-22(30)25-24(32)29(23(21)31)13-15-8-4-3-5-9-15/h3-11,14,18,26,30H,2,12-13H2,1H3,(H,25,32)/t18-/m1/s1

InChI Key

KUMYRAFTZRHBFE-GOSISDBHSA-N

MDL Number (MFCD)

MFCD27581995

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.918

Distribution Coefficient, logD

-2.692

Water Solubility, LogSw

-3.00

Polar Surface Area

82.700

Acid Dissociation Constant (pKa)

1.75

Base Dissociation Constant (pKb)

3.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.80

D364-0234 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D364-0234 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D364-0234?
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What is the minimum amount of D364-0234 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D364-0234
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D364-0234
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D364-0234 available by request