D364-0644 Screening compound: 5-[1-acetyl-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

D364-0644 Screening compound: 5-[1-acetyl-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
D364-0644 Screening compound: 5-[1-acetyl-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D364-0644
5-[1-acetyl-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D364-0644

Molecular Formula

C17H17ClN4O4 (C17 H17 ClN4 O4)

Compound Name

5-[1-acetyl-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-6-hydroxy-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

5-[1-acetyl-5-(4-chlorophenyl)-45-dihydro-1H-pyrazol-3-yl]-6-hydroxy-13-dimethyl-1234-tetrahydropyrimidine-24-dione

SMILES

CC(N(C(C1)c(cc2)ccc2Cl)N=C1C(C(N(C)C(N1C)=O)=O)=C1O)=O

InChI

InChI=1S/C17H17ClN4O4/c1-9(23)22-13(10-4-6-11(18)7-5-10)8-12(19-22)14-15(24)20(2)17(26)21(3)16(14)25/h4-7,13,24H,8H2,1-3H3/t13-/m0/s1

InChI Key

ALVCHJKFOWYSHA-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD27582115

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.8

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.814

Distribution Coefficient, logD

-2.428

Water Solubility, LogSw

-2.67

Polar Surface Area

75.828

Acid Dissociation Constant (pKa)

3.16

Base Dissociation Constant (pKb)

-2.44

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.40

D364-0644 in Drug Discovery

Included in Screening Libraries

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D364-0644 chemical compound. It will be published here after verification.

Frequently Asked Questions

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What is the minimum amount of D364-0644 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D364-0644
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D364-0644
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D364-0644 available by request