D364-1207 Screening compound: 6-hydroxy-5-[5-(3-hydroxy-4-methoxyphenyl)-1-propanoyl-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

D364-1207 Screening compound: 6-hydroxy-5-[5-(3-hydroxy-4-methoxyphenyl)-1-propanoyl-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
D364-1207 Screening compound: 6-hydroxy-5-[5-(3-hydroxy-4-methoxyphenyl)-1-propanoyl-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D364-1207
6-hydroxy-5-[5-(3-hydroxy-4-methoxyphenyl)-1-propanoyl-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D364-1207

Molecular Formula

C19H22N4O6 (C19 H22 N4 O6)

Compound Name

6-hydroxy-5-[5-(3-hydroxy-4-methoxyphenyl)-1-propanoyl-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-hydroxy-5-[5-(3-hydroxy-4-methoxyphenyl)-1-propanoyl-45-dihydro-1H-pyrazol-3-yl]-13-dimethyl-1234-tetrahydropyrimidine-24-dione

SMILES

CCC(N(C(C1)c(cc2)cc(O)c2OC)N=C1C(C(N(C)C(N1C)=O)=O)=C1O)=O

InChI

InChI=1S/C19H22N4O6/c1-5-15(25)23-12(10-6-7-14(29-4)13(24)8-10)9-11(20-23)16-17(26)21(2)19(28)22(3)18(16)27/h6-8,12,24,26H,5,9H2,1-4H3/t12-/m1/s1

InChI Key

VHOFOHGEUWVMHE-GFCCVEGCSA-N

MDL Number (MFCD)

MFCD27582269

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.41

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.157

Distribution Coefficient, logD

-3.085

Water Solubility, LogSw

-2.00

Polar Surface Area

99.011

Acid Dissociation Constant (pKa)

3.16

Base Dissociation Constant (pKb)

-1.38

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.80

D364-1207 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with D364-1207 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D364-1207?
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What is the minimum amount of D364-1207 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D364-1207
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D364-1207
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D364-1207 available by request