D364-1537 Screening compound: 6-hydroxy-3-(2-methoxyphenyl)-5-[1-propanoyl-5-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

D364-1537 Screening compound: 6-hydroxy-3-(2-methoxyphenyl)-5-[1-propanoyl-5-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
D364-1537 Screening compound: 6-hydroxy-3-(2-methoxyphenyl)-5-[1-propanoyl-5-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D364-1537
6-hydroxy-3-(2-methoxyphenyl)-5-[1-propanoyl-5-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D364-1537

Molecular Formula

C22H21N5O5 (C22 H21 N5 O5)

Compound Name

6-hydroxy-3-(2-methoxyphenyl)-5-[1-propanoyl-5-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-3-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-hydroxy-3-(2-methoxyphenyl)-5-[1-propanoyl-5-(pyridin-3-yl)-45-dihydro-1H-pyrazol-3-yl]-1234-tetrahydropyrimidine-24-dione

SMILES

CCC(N(C(C1)c2cnccc2)N=C1C(C(N(c(cccc1)c1OC)C(N1)=O)=O)=C1O)=O

InChI

InChI=1S/C22H21N5O5/c1-3-18(28)27-16(13-7-6-10-23-12-13)11-14(25-27)19-20(29)24-22(31)26(21(19)30)15-8-4-5-9-17(15)32-2/h4-10,12,16,29H,3,11H2,1-2H3,(H,24,31)/t16-/m1/s1

InChI Key

ZXFJWEGOYGOCNF-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD27582351

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.44

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.908

Distribution Coefficient, logD

-4.524

Water Solubility, LogSw

-1.35

Polar Surface Area

99.507

Acid Dissociation Constant (pKa)

1.97

Base Dissociation Constant (pKb)

4.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.70

D364-1537 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with D364-1537 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D364-1537?
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What is the minimum amount of D364-1537 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D364-1537
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D364-1537
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D364-1537 available by request