D367-0056 Screening compound: 7-(2,4-dimethoxyphenyl)-2-(phenylamino)-5,6,7,8-tetrahydroquinazolin-5-one

D367-0056 Screening compound: 7-(2,4-dimethoxyphenyl)-2-(phenylamino)-5,6,7,8-tetrahydroquinazolin-5-one
D367-0056 Screening compound: 7-(2,4-dimethoxyphenyl)-2-(phenylamino)-5,6,7,8-tetrahydroquinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D367-0056
7-(2,4-dimethoxyphenyl)-2-(phenylamino)-5,6,7,8-tetrahydroquinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D367-0056

Molecular Formula

C22H21N3O3 (C22 H21 N3 O3)

Compound Name

7-(2,4-dimethoxyphenyl)-2-(phenylamino)-5,6,7,8-tetrahydroquinazolin-5-one

IUPAC name

7-(24-dimethoxyphenyl)-2-(phenylamino)-5678-tetrahydroquinazolin-5-one

SMILES

COc1cc(OC)c(C(Cc2c3cnc(Nc4ccccc4)n2)CC3=O)cc1

InChI

InChI=1S/C22H21N3O3/c1-27-16-8-9-17(21(12-16)28-2)14-10-19-18(20(26)11-14)13-23-22(25-19)24-15-6-4-3-5-7-15/h3-9,12-14H,10-11H2,1-2H3,(H,23,24,25)/t14-/m1/s1

InChI Key

PFTBRNFUNVVUPQ-CQSZACIVSA-N

MDL Number (MFCD)

MFCD09784562

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.237

Distribution Coefficient, logD

4.237

Water Solubility, LogSw

-4.31

Polar Surface Area

58.950

Acid Dissociation Constant (pKa)

16.67

Base Dissociation Constant (pKb)

0.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.70

D367-0056 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D367-0056 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D367-0056?
Check Price and Availability of D367-0056, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D367-0056 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D367-0056
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D367-0056
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D367-0056 available by request