D367-0127 Screening compound: 4-methyl-7-(4-methylphenyl)-2-[(4-methylphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one

D367-0127 Screening compound: 4-methyl-7-(4-methylphenyl)-2-[(4-methylphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one
D367-0127 Screening compound: 4-methyl-7-(4-methylphenyl)-2-[(4-methylphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D367-0127
4-methyl-7-(4-methylphenyl)-2-[(4-methylphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D367-0127

Molecular Formula

C23H23N3O (C23 H23 N3 O)

Compound Name

4-methyl-7-(4-methylphenyl)-2-[(4-methylphenyl)amino]-5,6,7,8-tetrahydroquinazolin-5-one

IUPAC name

4-methyl-7-(4-methylphenyl)-2-[(4-methylphenyl)amino]-5678-tetrahydroquinazolin-5-one

SMILES

Cc1ccc(C(Cc2c3c(C)nc(Nc4ccc(C)cc4)n2)CC3=O)cc1

InChI

InChI=1S/C23H23N3O/c1-14-4-8-17(9-5-14)18-12-20-22(21(27)13-18)16(3)24-23(26-20)25-19-10-6-15(2)7-11-19/h4-11,18H,12-13H2,1-3H3,(H,24,25,26)/t18-/m1/s1

InChI Key

XBGCROBYEOMNJP-GOSISDBHSA-N

MDL Number (MFCD)

MFCD08709220

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.743

Distribution Coefficient, logD

5.743

Water Solubility, LogSw

-5.60

Polar Surface Area

43.831

Acid Dissociation Constant (pKa)

16.67

Base Dissociation Constant (pKb)

1.30

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.10

D367-0127 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D367-0127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D367-0127?
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What is the minimum amount of D367-0127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D367-0127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D367-0127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D367-0127 available by request