D367-0181 Screening compound: 7-(4-methoxyphenyl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methyl-5,6,7,8-tetrahydroquinazolin-5-one

D367-0181 Screening compound: 7-(4-methoxyphenyl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methyl-5,6,7,8-tetrahydroquinazolin-5-one
D367-0181 Screening compound: 7-(4-methoxyphenyl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methyl-5,6,7,8-tetrahydroquinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D367-0181
7-(4-methoxyphenyl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methyl-5,6,7,8-tetrahydroquinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D367-0181

Molecular Formula

C27H30N4O3 (C27 H30 N4 O3)

Compound Name

7-(4-methoxyphenyl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methyl-5,6,7,8-tetrahydroquinazolin-5-one

IUPAC name

7-(4-methoxyphenyl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methyl-5678-tetrahydroquinazolin-5-one

SMILES

Cc1nc(N(CC2)CCN2c(cc2)ccc2OC)nc(CC(C2)c(cc3)ccc3OC)c1C2=O

InChI

InChI=1S/C27H30N4O3/c1-18-26-24(16-20(17-25(26)32)19-4-8-22(33-2)9-5-19)29-27(28-18)31-14-12-30(13-15-31)21-6-10-23(34-3)11-7-21/h4-11,20H,12-17H2,1-3H3/t20-/m1/s1

InChI Key

GQVMXUACLXKJIR-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD08709241

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.223

Distribution Coefficient, logD

5.223

Water Solubility, LogSw

-5.27

Polar Surface Area

54.512

Acid Dissociation Constant (pKa)

16.67

Base Dissociation Constant (pKb)

8.09

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.00

D367-0181 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Autophagy-Targeted Library (4564 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system

References: we are preparing a list of scientific research reports with D367-0181 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D367-0181?
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What is the minimum amount of D367-0181 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D367-0181
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D367-0181
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D367-0181 available by request