D367-0283 Screening compound: 7-(2,4-dimethoxyphenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one

D367-0283 Screening compound: 7-(2,4-dimethoxyphenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one
D367-0283 Screening compound: 7-(2,4-dimethoxyphenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D367-0283
7-(2,4-dimethoxyphenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D367-0283

Molecular Formula

C25H27N5O3 (C25 H27 N5 O3)

Compound Name

7-(2,4-dimethoxyphenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one

IUPAC name

7-(24-dimethoxyphenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5678-tetrahydroquinazolin-5-one

SMILES

COc1cc(OC)c(C(Cc2c3cnc(N(CC4)CCN4c4ncccc4)n2)CC3=O)cc1

InChI

InChI=1S/C25H27N5O3/c1-32-18-6-7-19(23(15-18)33-2)17-13-21-20(22(31)14-17)16-27-25(28-21)30-11-9-29(10-12-30)24-5-3-4-8-26-24/h3-8,15-17H,9-14H2,1-2H3/t17-/m1/s1

InChI Key

WVIVEPOJYZATJZ-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD08591642

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.068

Distribution Coefficient, logD

4.062

Water Solubility, LogSw

-4.13

Polar Surface Area

63.054

Acid Dissociation Constant (pKa)

16.67

Base Dissociation Constant (pKb)

5.52

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.00

D367-0283 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with D367-0283 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D367-0283?
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What is the minimum amount of D367-0283 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D367-0283
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D367-0283
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D367-0283 available by request