D367-0289 Screening compound: 7-(4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one

D367-0289 Screening compound: 7-(4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one
D367-0289 Screening compound: 7-(4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D367-0289
7-(4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D367-0289

Molecular Formula

C23H22ClN5O (C23 H22 ClN5 O)

Compound Name

7-(4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-5-one

IUPAC name

7-(4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]-5678-tetrahydroquinazolin-5-one

SMILES

O=C(CC(C1)c(cc2)ccc2Cl)c2c1nc(N(CC1)CCN1c1ncccc1)nc2

InChI

InChI=1S/C23H22ClN5O/c24-18-6-4-16(5-7-18)17-13-20-19(21(30)14-17)15-26-23(27-20)29-11-9-28(10-12-29)22-3-1-2-8-25-22/h1-8,15,17H,9-14H2/t17-/m0/s1

InChI Key

VABFXTXAIFZXHY-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD08747106

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.91

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.555

Distribution Coefficient, logD

4.549

Water Solubility, LogSw

-5.04

Polar Surface Area

47.880

Acid Dissociation Constant (pKa)

16.67

Base Dissociation Constant (pKb)

5.52

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.40

D367-0289 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with D367-0289 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D367-0289?
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What is the minimum amount of D367-0289 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D367-0289
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D367-0289
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D367-0289 available by request