D369-0383 Screening compound: 3-(tert-butyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one

D369-0383 Screening compound: 3-(tert-butyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one
D369-0383 Screening compound: 3-(tert-butyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D369-0383
3-(tert-butyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D369-0383

Molecular Formula

C19H21N3OS2 (C19 H21 N3 OS2)

Compound Name

3-(tert-butyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one

IUPAC name

5-tert-butyl-1113-dimethyl-4-(thiophen-2-yl)-8-thia-3510-triazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)911-tetraen-6-one

SMILES

CC(C)(C)N(C(c1cccs1)Nc1c2sc3nc(C)cc(C)c13)C2=O

InChI

InChI=1S/C19H21N3OS2/c1-10-9-11(2)20-17-13(10)14-15(25-17)18(23)22(19(3,4)5)16(21-14)12-7-6-8-24-12/h6-9,16,21H,1-5H3/t16-/m1/s1

InChI Key

NRBXNMKFAAKDFI-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD14825575

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.53

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.965

Distribution Coefficient, logD

3.936

Water Solubility, LogSw

-4.14

Polar Surface Area

35.991

Acid Dissociation Constant (pKa)

15.39

Base Dissociation Constant (pKb)

6.24

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.80

D369-0383 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

KRAS-Targeted Library (16000 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D369-0383 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D369-0383?
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What is the minimum amount of D369-0383 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D369-0383
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D369-0383
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D369-0383 available by request