D369-0384 Screening compound: 3-(4-fluorophenyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one

D369-0384 Screening compound: 3-(4-fluorophenyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one
D369-0384 Screening compound: 3-(4-fluorophenyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D369-0384
3-(4-fluorophenyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D369-0384

Molecular Formula

C21H16FN3OS2 (C21 H16 FN3 OS2)

Compound Name

3-(4-fluorophenyl)-7,9-dimethyl-2-(2-thienyl)-2,3-dihydropyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(1H)-one

IUPAC name

5-(4-fluorophenyl)-1113-dimethyl-4-(thiophen-2-yl)-8-thia-3510-triazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)911-tetraen-6-one

SMILES

Cc1c(c(NC(c2cccs2)N(c(cc2)ccc2F)C2=O)c2s2)c2nc(C)c1

InChI

InChI=1S/C21H16FN3OS2/c1-11-10-12(2)23-20-16(11)17-18(28-20)21(26)25(14-7-5-13(22)6-8-14)19(24-17)15-4-3-9-27-15/h3-10,19,24H,1-2H3/t19-/m1/s1

InChI Key

CEQZTPWZKRMEMA-LJQANCHMSA-N

MDL Number (MFCD)

MFCD14825576

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.51

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.471

Distribution Coefficient, logD

4.470

Water Solubility, LogSw

-4.55

Polar Surface Area

35.025

Acid Dissociation Constant (pKa)

13.44

Base Dissociation Constant (pKb)

4.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

14.30

D369-0384 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-infective Library (19449 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Immune system
  • animal
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with D369-0384 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D369-0384?
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What is the minimum amount of D369-0384 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D369-0384
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D369-0384
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D369-0384 available by request