D370-0458 Screening compound: N-[4-(4-ethoxy-3-methylphenyl)-1,2,5-oxadiazol-3-yl]-2-fluorobenzamide

D370-0458 Screening compound: N-[4-(4-ethoxy-3-methylphenyl)-1,2,5-oxadiazol-3-yl]-2-fluorobenzamide
D370-0458 Screening compound: N-[4-(4-ethoxy-3-methylphenyl)-1,2,5-oxadiazol-3-yl]-2-fluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D370-0458
N-[4-(4-ethoxy-3-methylphenyl)-1,2,5-oxadiazol-3-yl]-2-fluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D370-0458

Molecular Formula

C18H16FN3O3 (C18 H16 FN3 O3)

Compound Name

N-[4-(4-ethoxy-3-methylphenyl)-1,2,5-oxadiazol-3-yl]-2-fluorobenzamide

IUPAC name

N-[4-(4-ethoxy-3-methylphenyl)-125-oxadiazol-3-yl]-2-fluorobenzamide

SMILES

CCOc(cc1)c(C)cc1-c1nonc1NC(c(cccc1)c1F)=O

InChI

InChI=1S/C18H16FN3O3/c1-3-24-15-9-8-12(10-11(15)2)16-17(22-25-21-16)20-18(23)13-6-4-5-7-14(13)19/h4-10H,3H2,1-2H3,(H,20,22,23)

InChI Key

VZTBUUDHFIUKPD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12917938

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.34

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.514

Distribution Coefficient, logD

4.367

Water Solubility, LogSw

-4.39

Polar Surface Area

67.296

Acid Dissociation Constant (pKa)

7.79

Base Dissociation Constant (pKb)

-7.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

D370-0458 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Nuclear receptors
  • Kinases

References: we are preparing a list of scientific research reports with D370-0458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D370-0458?
Check Price and Availability of D370-0458, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D370-0458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D370-0458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D370-0458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D370-0458 available by request