D374-0100 Screening compound: 5-chloro-3,6-dimethyl-N-[4-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide

D374-0100 Screening compound: 5-chloro-3,6-dimethyl-N-[4-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide
D374-0100 Screening compound: 5-chloro-3,6-dimethyl-N-[4-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D374-0100
5-chloro-3,6-dimethyl-N-[4-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D374-0100

Molecular Formula

C18H14ClN5O2 (C18 H14 ClN5 O2)

Compound Name

5-chloro-3,6-dimethyl-N-[4-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide

IUPAC name

5-chloro-36-dimethyl-N-[4-(1H-1234-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide

SMILES

Cc(c1c2)c(C(Nc(cc3)ccc3-n3nnnc3)=O)oc1cc(C)c2Cl

InChI

InChI=1S/C18H14ClN5O2/c1-10-7-16-14(8-15(10)19)11(2)17(26-16)18(25)21-12-3-5-13(6-4-12)24-9-20-22-23-24/h3-9H,1-2H3,(H,21,25)

InChI Key

FGMWBDKTAFKXNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12920152

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.79

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.795

Distribution Coefficient, logD

4.795

Water Solubility, LogSw

-4.93

Polar Surface Area

71.621

Acid Dissociation Constant (pKa)

10.80

Base Dissociation Constant (pKb)

2.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

D374-0100 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • Kinases
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D374-0100 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D374-0100?
Check Price and Availability of D374-0100, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D374-0100 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D374-0100
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D374-0100
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D374-0100 available by request