D374-0129 Screening compound: N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)thiophene-2-carboxamide

D374-0129 Screening compound: N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)thiophene-2-carboxamide
D374-0129 Screening compound: N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D374-0129
N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D374-0129

Molecular Formula

C13H10N2O3S (C13 H10 N2 O3 S)

Compound Name

N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)thiophene-2-carboxamide

IUPAC name

N-(3-oxo-34-dihydro-2H-14-benzoxazin-6-yl)thiophene-2-carboxamide

SMILES

O=C(c1cccs1)Nc(cc1)cc(N2)c1OCC2=O

InChI

InChI=1S/C13H10N2O3S/c16-12-7-18-10-4-3-8(6-9(10)15-12)14-13(17)11-2-1-5-19-11/h1-6H,7H2,(H,14,17)(H,15,16)

InChI Key

GPUDDFJNMXXEET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10062140

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

274.3

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.804

Distribution Coefficient, logD

1.804

Water Solubility, LogSw

-2.53

Polar Surface Area

57.618

Acid Dissociation Constant (pKa)

10.83

Base Dissociation Constant (pKb)

2.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.70

D374-0129 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Fragments Library (11262 compounds)

KRAS-Targeted Library (16000 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Mechanism of action:
  • Epigenetic
Structure:
  • Fragments
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D374-0129 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D374-0129?
Check Price and Availability of D374-0129, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D374-0129 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D374-0129
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D374-0129
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D374-0129 available by request