D374-0138 Screening compound: 2-(2,6-dimethylphenoxy)-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)acetamide

D374-0138 Screening compound: 2-(2,6-dimethylphenoxy)-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)acetamide
D374-0138 Screening compound: 2-(2,6-dimethylphenoxy)-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D374-0138
2-(2,6-dimethylphenoxy)-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D374-0138

Molecular Formula

C18H18N2O4 (C18 H18 N2 O4)

Compound Name

2-(2,6-dimethylphenoxy)-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)acetamide

IUPAC name

2-(26-dimethylphenoxy)-N-(3-oxo-34-dihydro-2H-14-benzoxazin-6-yl)acetamide

SMILES

Cc1cccc(C)c1OCC(Nc(cc1)cc(N2)c1OCC2=O)=O

InChI

InChI=1S/C18H18N2O4/c1-11-4-3-5-12(2)18(11)24-10-16(21)19-13-6-7-15-14(8-13)20-17(22)9-23-15/h3-8H,9-10H2,1-2H3,(H,19,21)(H,20,22)

InChI Key

JACWDEMWZAATSX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10068580

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.35

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.885

Distribution Coefficient, logD

2.885

Water Solubility, LogSw

-3.16

Polar Surface Area

64.059

Acid Dissociation Constant (pKa)

11.39

Base Dissociation Constant (pKb)

-0.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

D374-0138 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D374-0138 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D374-0138?
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What is the minimum amount of D374-0138 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D374-0138
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D374-0138
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D374-0138 available by request