D374-0172 Screening compound: 3-chloro-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)benzamide

D374-0172 Screening compound: 3-chloro-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)benzamide
D374-0172 Screening compound: 3-chloro-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D374-0172
3-chloro-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D374-0172

Molecular Formula

C15H11ClN2O3 (C15 H11 ClN2 O3)

Compound Name

3-chloro-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)benzamide

IUPAC name

3-chloro-N-(3-oxo-34-dihydro-2H-14-benzoxazin-6-yl)benzamide

SMILES

O=C(c1cccc(Cl)c1)Nc(cc1)cc(N2)c1OCC2=O

InChI

InChI=1S/C15H11ClN2O3/c16-10-3-1-2-9(6-10)15(20)17-11-4-5-13-12(7-11)18-14(19)8-21-13/h1-7H,8H2,(H,17,20)(H,18,19)

InChI Key

ZFABGXMDODWAOO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10067447

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

302.72

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.554

Distribution Coefficient, logD

2.544

Water Solubility, LogSw

-3.25

Polar Surface Area

56.600

Acid Dissociation Constant (pKa)

9.04

Base Dissociation Constant (pKb)

-1.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.70

D374-0172 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Glucocorticoid receptors Library (4806 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D374-0172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D374-0172?
Check Price and Availability of D374-0172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D374-0172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D374-0172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D374-0172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D374-0172 available by request