D376-0584 Screening compound: 2-{2-[(4-chloro-3-methylphenoxy)methyl]-1,3-thiazol-4-yl}-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide

D376-0584 Screening compound: 2-{2-[(4-chloro-3-methylphenoxy)methyl]-1,3-thiazol-4-yl}-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide
D376-0584 Screening compound: 2-{2-[(4-chloro-3-methylphenoxy)methyl]-1,3-thiazol-4-yl}-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D376-0584
2-{2-[(4-chloro-3-methylphenoxy)methyl]-1,3-thiazol-4-yl}-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D376-0584

Molecular Formula

C23H20ClN3O2S2 (C23 H20 ClN3 O2 S2)

Compound Name

2-{2-[(4-chloro-3-methylphenoxy)methyl]-1,3-thiazol-4-yl}-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide

IUPAC name

2-{2-[(4-chloro-3-methylphenoxy)methyl]-13-thiazol-4-yl}-N-[4-(4-methylphenyl)-13-thiazol-2-yl]acetamide

SMILES

Cc(cc1)ccc1-c1csc(NC(Cc2csc(COc(cc3)cc(C)c3Cl)n2)=O)n1

InChI

InChI=1S/C23H20ClN3O2S2/c1-14-3-5-16(6-4-14)20-13-31-23(26-20)27-21(28)10-17-12-30-22(25-17)11-29-18-7-8-19(24)15(2)9-18/h3-9,12-13H,10-11H2,1-2H3,(H,26,27,28)

InChI Key

MHXXCOUFKXKMBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09540933

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.02

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

7.173

Distribution Coefficient, logD

7.173

Water Solubility, LogSw

-6.45

Polar Surface Area

51.115

Acid Dissociation Constant (pKa)

11.57

Base Dissociation Constant (pKb)

0.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

D376-0584 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D376-0584 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D376-0584?
Check Price and Availability of D376-0584, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D376-0584 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D376-0584
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D376-0584
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D376-0584 available by request