D376-1099 Screening compound: 2-[(3,4-dimethylphenoxy)methyl]-4-methyl-N-(1,3,4-thiadiazol-2-yl)-1,3-thiazole-5-carboxamide

D376-1099 Screening compound: 2-[(3,4-dimethylphenoxy)methyl]-4-methyl-N-(1,3,4-thiadiazol-2-yl)-1,3-thiazole-5-carboxamide
D376-1099 Screening compound: 2-[(3,4-dimethylphenoxy)methyl]-4-methyl-N-(1,3,4-thiadiazol-2-yl)-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D376-1099
2-[(3,4-dimethylphenoxy)methyl]-4-methyl-N-(1,3,4-thiadiazol-2-yl)-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D376-1099

Molecular Formula

C16H16N4O2S2 (C16 H16 N4 O2 S2)

Compound Name

2-[(3,4-dimethylphenoxy)methyl]-4-methyl-N-(1,3,4-thiadiazol-2-yl)-1,3-thiazole-5-carboxamide

IUPAC name

2-[(34-dimethylphenoxy)methyl]-4-methyl-N-(134-thiadiazol-2-yl)-13-thiazole-5-carboxamide

SMILES

Cc1c(C(Nc2nncs2)=O)sc(COc2cc(C)c(C)cc2)n1

InChI

InChI=1S/C16H16N4O2S2/c1-9-4-5-12(6-10(9)2)22-7-13-18-11(3)14(24-13)15(21)19-16-20-17-8-23-16/h4-6,8H,7H2,1-3H3,(H,19,20,21)

InChI Key

XLYCBEOKDQESSP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27582540

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.781

Distribution Coefficient, logD

3.597

Water Solubility, LogSw

-3.96

Polar Surface Area

65.210

Acid Dissociation Constant (pKa)

7.68

Base Dissociation Constant (pKb)

-1.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

D376-1099 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D376-1099 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D376-1099?
Check Price and Availability of D376-1099, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D376-1099 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D376-1099
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D376-1099
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D376-1099 available by request