D377-0028 Screening compound: 2-[(1E)-2-(3-fluorophenyl)ethenyl]quinolin-8-ol

D377-0028 Screening compound: 2-[(1E)-2-(3-fluorophenyl)ethenyl]quinolin-8-ol
D377-0028 Screening compound: 2-[(1E)-2-(3-fluorophenyl)ethenyl]quinolin-8-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound D377-0028
2-[(1E)-2-(3-fluorophenyl)ethenyl]quinolin-8-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D377-0028

Molecular Formula

C17H12FNO (C17 H12 FNO)

Compound Name

2-[(1E)-2-(3-fluorophenyl)ethenyl]quinolin-8-ol

IUPAC name

2-[(1E)-2-(3-fluorophenyl)ethenyl]quinolin-8-ol

SMILES

Oc1c2nc(/C=C/c3cccc(F)c3)ccc2ccc1

InChI

InChI=1S/C17H12FNO/c18-14-5-1-3-12(11-14)7-9-15-10-8-13-4-2-6-16(20)17(13)19-15/h1-11,20H

InChI Key

SZKQDIDKTUDYEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03999814

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

265.29

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

4.500

Distribution Coefficient, logD

4.496

Water Solubility, LogSw

-4.35

Polar Surface Area

26.111

Acid Dissociation Constant (pKa)

9.41

Base Dissociation Constant (pKb)

3.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

D377-0028 in Drug Discovery

Included in Screening Libraries

?ysteine Targeted Covalent Library (39471 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Targets:
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D377-0028 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D377-0028?
Check Price and Availability of D377-0028, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D377-0028 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D377-0028
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D377-0028
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D377-0028 available by request