D381-0103 Screening compound: N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]-2-methoxybenzamide

D381-0103 Screening compound: N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]-2-methoxybenzamide
D381-0103 Screening compound: N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]-2-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D381-0103
N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]-2-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D381-0103

Molecular Formula

C18H17N3O4S (C18 H17 N3 O4 S)

Compound Name

N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]-2-methoxybenzamide

IUPAC name

N-[3-(34-dimethoxyphenyl)-124-thiadiazol-5-yl]-2-methoxybenzamide

SMILES

COc(cccc1)c1C(Nc1nc(-c(cc2)cc(OC)c2OC)ns1)=O

InChI

InChI=1S/C18H17N3O4S/c1-23-13-7-5-4-6-12(13)17(22)20-18-19-16(21-26-18)11-8-9-14(24-2)15(10-11)25-3/h4-10H,1-3H3,(H,19,20,21,22)

InChI Key

VUNQZQHDLYPVLY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12915985

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.479

Distribution Coefficient, logD

3.387

Water Solubility, LogSw

-3.93

Polar Surface Area

66.808

Acid Dissociation Constant (pKa)

8.03

Base Dissociation Constant (pKb)

-3.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

D381-0103 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D381-0103 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D381-0103?
Check Price and Availability of D381-0103, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D381-0103 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D381-0103
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D381-0103
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D381-0103 available by request