D381-0150 Screening compound: 2-(4-tert-butylphenoxy)-N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]acetamide

D381-0150 Screening compound: 2-(4-tert-butylphenoxy)-N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]acetamide
D381-0150 Screening compound: 2-(4-tert-butylphenoxy)-N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D381-0150
2-(4-tert-butylphenoxy)-N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D381-0150

Molecular Formula

C22H25N3O4S (C22 H25 N3 O4 S)

Compound Name

2-(4-tert-butylphenoxy)-N-[3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazol-5-yl]acetamide

IUPAC name

2-(4-tert-butylphenoxy)-N-[3-(34-dimethoxyphenyl)-124-thiadiazol-5-yl]acetamide

SMILES

CC(C)(C)c(cc1)ccc1OCC(Nc1nc(-c(cc2)cc(OC)c2OC)ns1)=O

InChI

InChI=1S/C22H25N3O4S/c1-22(2,3)15-7-9-16(10-8-15)29-13-19(26)23-21-24-20(25-30-21)14-6-11-17(27-4)18(12-14)28-5/h6-12H,13H2,1-5H3,(H,23,24,25,26)

InChI Key

KHSYUNXLLWVYLG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12917364

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.383

Distribution Coefficient, logD

5.383

Water Solubility, LogSw

-5.45

Polar Surface Area

66.464

Acid Dissociation Constant (pKa)

10.77

Base Dissociation Constant (pKb)

-4.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

D381-0150 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D381-0150 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D381-0150?
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What is the minimum amount of D381-0150 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D381-0150
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D381-0150
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D381-0150 available by request