D381-0461 Screening compound: 2-(3-chlorophenoxy)-N-(2-methylquinolin-8-yl)acetamide

D381-0461 Screening compound: 2-(3-chlorophenoxy)-N-(2-methylquinolin-8-yl)acetamide
D381-0461 Screening compound: 2-(3-chlorophenoxy)-N-(2-methylquinolin-8-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D381-0461
2-(3-chlorophenoxy)-N-(2-methylquinolin-8-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D381-0461

Molecular Formula

C18H15ClN2O2 (C18 H15 ClN2 O2)

Compound Name

2-(3-chlorophenoxy)-N-(2-methylquinolin-8-yl)acetamide

IUPAC name

2-(3-chlorophenoxy)-N-(2-methylquinolin-8-yl)acetamide

SMILES

Cc1ccc(cccc2NC(COc3cccc(Cl)c3)=O)c2n1

InChI

InChI=1S/C18H15ClN2O2/c1-12-8-9-13-4-2-7-16(18(13)20-12)21-17(22)11-23-15-6-3-5-14(19)10-15/h2-10H,11H2,1H3,(H,21,22)

InChI Key

BJPQLZQYPPTKHO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12914443

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.78

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.396

Distribution Coefficient, logD

4.395

Water Solubility, LogSw

-4.48

Polar Surface Area

38.825

Acid Dissociation Constant (pKa)

11.27

Base Dissociation Constant (pKb)

4.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

D381-0461 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Cardiovascular Library (22201 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D381-0461 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D381-0461?
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What is the minimum amount of D381-0461 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D381-0461
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D381-0461
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D381-0461 available by request