D393-0145 Screening compound: 2-(3,4-dimethoxyphenyl)-5-methyl-N-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine

D393-0145 Screening compound: 2-(3,4-dimethoxyphenyl)-5-methyl-N-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine
D393-0145 Screening compound: 2-(3,4-dimethoxyphenyl)-5-methyl-N-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D393-0145
2-(3,4-dimethoxyphenyl)-5-methyl-N-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D393-0145

Molecular Formula

C22H22N4O2 (C22 H22 N4 O2)

Compound Name

2-(3,4-dimethoxyphenyl)-5-methyl-N-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine

IUPAC name

2-(34-dimethoxyphenyl)-5-methyl-N-(4-methylphenyl)pyrazolo[15-a]pyrimidin-7-amine

SMILES

Cc(cc1)ccc1Nc1cc(C)nc2cc(-c(cc3)cc(OC)c3OC)nn12

InChI

InChI=1S/C22H22N4O2/c1-14-5-8-17(9-6-14)24-21-11-15(2)23-22-13-18(25-26(21)22)16-7-10-19(27-3)20(12-16)28-4/h5-13,24H,1-4H3

InChI Key

LRGQRCGCMSGVMI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10478703

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.679

Distribution Coefficient, logD

3.765

Water Solubility, LogSw

-4.47

Polar Surface Area

43.718

Acid Dissociation Constant (pKa)

18.41

Base Dissociation Constant (pKb)

8.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

D393-0145 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D393-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D393-0145?
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What is the minimum amount of D393-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D393-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D393-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D393-0145 available by request