D393-0289 Screening compound: 3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine

D393-0289 Screening compound: 3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine
D393-0289 Screening compound: 3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D393-0289
3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D393-0289

Molecular Formula

C19H21ClF3N5 (C19 H21 ClF3 N5)

Compound Name

3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine

IUPAC name

3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-5-methyl-2-(trifluoromethyl)pyrazolo[15-a]pyrimidin-7-amine

SMILES

Cc(cc(NCCCN(C)C)n1nc2C(F)(F)F)nc1c2-c(cc1)ccc1Cl

InChI

InChI=1S/C19H21ClF3N5/c1-12-11-15(24-9-4-10-27(2)3)28-18(25-12)16(17(26-28)19(21,22)23)13-5-7-14(20)8-6-13/h5-8,11,24H,4,9-10H2,1-3H3

InChI Key

CTYRHALKHOOTGN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10478813

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.86

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.016

Distribution Coefficient, logD

2.080

Water Solubility, LogSw

-4.75

Polar Surface Area

35.074

Acid Dissociation Constant (pKa)

19.31

Base Dissociation Constant (pKb)

9.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

D393-0289 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D393-0289 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D393-0289?
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What is the minimum amount of D393-0289 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D393-0289
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D393-0289
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D393-0289 available by request