D393-0327 Screening compound: 1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine

D393-0327 Screening compound: 1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine
D393-0327 Screening compound: 1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound D393-0327
1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D393-0327

Molecular Formula

C19H18ClF3N4 (C19 H18 ClF3 N4)

Compound Name

1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]piperidine

IUPAC name

1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[15-a]pyrimidin-7-yl]piperidine

SMILES

Cc(cc(n1nc2C(F)(F)F)N3CCCCC3)nc1c2-c(cccc1)c1Cl

InChI

InChI=1S/C19H18ClF3N4/c1-12-11-15(26-9-5-2-6-10-26)27-18(24-12)16(17(25-27)19(21,22)23)13-7-3-4-8-14(13)20/h3-4,7-8,11H,2,5-6,9-10H2,1H3

InChI Key

UBBHLIRAVMRUJE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10478833

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.83

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.238

Distribution Coefficient, logD

5.138

Water Solubility, LogSw

-5.92

Polar Surface Area

23.050

Acid Dissociation Constant (pKa)

25.34

Base Dissociation Constant (pKb)

6.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

D393-0327 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GABA Library (7115 compounds)

New Agro Library (44492 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Ion Channels
  • Phosphatases
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D393-0327 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D393-0327?
Check Price and Availability of D393-0327, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D393-0327 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D393-0327
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D393-0327
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D393-0327 available by request