D401-0381 Screening compound: 2-(3,4-dimethoxyphenyl)-N-(2,6-dimethylphenyl)imidazo[1,2-a]pyrazin-3-amine

D401-0381 Screening compound: 2-(3,4-dimethoxyphenyl)-N-(2,6-dimethylphenyl)imidazo[1,2-a]pyrazin-3-amine
D401-0381 Screening compound: 2-(3,4-dimethoxyphenyl)-N-(2,6-dimethylphenyl)imidazo[1,2-a]pyrazin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D401-0381
2-(3,4-dimethoxyphenyl)-N-(2,6-dimethylphenyl)imidazo[1,2-a]pyrazin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D401-0381

Molecular Formula

C22H22N4O2 (C22 H22 N4 O2)

Compound Name

2-(3,4-dimethoxyphenyl)-N-(2,6-dimethylphenyl)imidazo[1,2-a]pyrazin-3-amine

IUPAC name

2-(34-dimethoxyphenyl)-N-(26-dimethylphenyl)imidazo[12-a]pyrazin-3-amine

SMILES

Cc1cccc(C)c1Nc1c(-c(cc2)cc(OC)c2OC)nc2n1ccnc2

InChI

InChI=1S/C22H22N4O2/c1-14-6-5-7-15(2)20(14)25-22-21(24-19-13-23-10-11-26(19)22)16-8-9-17(27-3)18(12-16)28-4/h5-13,25H,1-4H3

InChI Key

DNMHFGLPRHMUAK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27584269

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.461

Distribution Coefficient, logD

3.410

Water Solubility, LogSw

-3.36

Polar Surface Area

41.062

Acid Dissociation Constant (pKa)

19.88

Base Dissociation Constant (pKb)

6.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

D401-0381 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antifungal Library (16415 compounds)

Antimitotic Tubulin Library (17355 compounds)

Nucleic Acid Ligands (8311 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • Epigenetic
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D401-0381 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D401-0381?
Check Price and Availability of D401-0381, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D401-0381 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D401-0381
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D401-0381
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D401-0381 available by request