D404-0270 Screening compound: 1-[4-(4-chlorobenzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]-4-(3-fluorobenzoyl)piperazine

D404-0270 Screening compound: 1-[4-(4-chlorobenzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]-4-(3-fluorobenzoyl)piperazine
D404-0270 Screening compound: 1-[4-(4-chlorobenzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]-4-(3-fluorobenzoyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound D404-0270
1-[4-(4-chlorobenzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]-4-(3-fluorobenzoyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D404-0270

Molecular Formula

C24H19ClFN3O5S (C24 H19 ClFN3 O5 S)

Compound Name

1-[4-(4-chlorobenzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]-4-(3-fluorobenzoyl)piperazine

IUPAC name

1-[4-(4-chlorobenzenesulfonyl)-2-(furan-2-yl)-13-oxazol-5-yl]-4-(3-fluorobenzoyl)piperazine

SMILES

O=C(c1cc(F)ccc1)N(CC1)CCN1c(oc(-c1ccco1)n1)c1S(c(cc1)ccc1Cl)(=O)=O

InChI

InChI=1S/C24H19ClFN3O5S/c25-17-6-8-19(9-7-17)35(31,32)22-24(34-21(27-22)20-5-2-14-33-20)29-12-10-28(11-13-29)23(30)16-3-1-4-18(26)15-16/h1-9,14-15H,10-13H2

InChI Key

HTFRRBMUDXXOLI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27584511

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

515.95

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.159

Distribution Coefficient, logD

4.159

Water Solubility, LogSw

-4.54

Polar Surface Area

76.513

Acid Dissociation Constant (pKa)

27.36

Base Dissociation Constant (pKb)

-4.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

D404-0270 in Drug Discovery

Included in Screening Libraries

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with D404-0270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D404-0270?
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What is the minimum amount of D404-0270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D404-0270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D404-0270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D404-0270 available by request