D408-0022 Screening compound: ethyl 2-(4-{[(4-phenyl-1,3-thiazol-2-yl)carbamoyl]amino}phenyl)acetate

D408-0022 Screening compound: ethyl 2-(4-{[(4-phenyl-1,3-thiazol-2-yl)carbamoyl]amino}phenyl)acetate
D408-0022 Screening compound: ethyl 2-(4-{[(4-phenyl-1,3-thiazol-2-yl)carbamoyl]amino}phenyl)acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound D408-0022
ethyl 2-(4-{[(4-phenyl-1,3-thiazol-2-yl)carbamoyl]amino}phenyl)acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D408-0022

Molecular Formula

C20H19N3O3S (C20 H19 N3 O3 S)

Compound Name

ethyl 2-(4-{[(4-phenyl-1,3-thiazol-2-yl)carbamoyl]amino}phenyl)acetate

IUPAC name

ethyl 2-(4-{[(4-phenyl-13-thiazol-2-yl)carbamoyl]amino}phenyl)acetate

SMILES

CCOC(Cc(cc1)ccc1NC(Nc1nc(-c2ccccc2)cs1)=O)=O

InChI

InChI=1S/C20H19N3O3S/c1-2-26-18(24)12-14-8-10-16(11-9-14)21-19(25)23-20-22-17(13-27-20)15-6-4-3-5-7-15/h3-11,13H,2,12H2,1H3,(H2,21,22,23,25)

InChI Key

PFDXCYWKVQEFDM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14827726

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.076

Distribution Coefficient, logD

5.076

Water Solubility, LogSw

-4.75

Polar Surface Area

62.475

Acid Dissociation Constant (pKa)

12.66

Base Dissociation Constant (pKb)

1.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

D408-0022 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Integrin Receptors Targeted library (1715 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Immune system
Targets:
  • Kinases
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D408-0022 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D408-0022?
Check Price and Availability of D408-0022, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D408-0022 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D408-0022
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D408-0022
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D408-0022 available by request