D411-0374 Screening compound: ethyl 1-{[2-(furan-2-amido)-5-methylthiophen-3-yl](4-methoxyphenyl)methyl}piperidine-4-carboxylate

D411-0374 Screening compound: ethyl 1-{[2-(furan-2-amido)-5-methylthiophen-3-yl](4-methoxyphenyl)methyl}piperidine-4-carboxylate
D411-0374 Screening compound: ethyl 1-{[2-(furan-2-amido)-5-methylthiophen-3-yl](4-methoxyphenyl)methyl}piperidine-4-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D411-0374
ethyl 1-{[2-(furan-2-amido)-5-methylthiophen-3-yl](4-methoxyphenyl)methyl}piperidine-4-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D411-0374

Molecular Formula

C26H30N2O5S (C26 H30 N2 O5 S)

Compound Name

ethyl 1-{[2-(furan-2-amido)-5-methylthiophen-3-yl](4-methoxyphenyl)methyl}piperidine-4-carboxylate

IUPAC name

ethyl 1-{[2-(furan-2-amido)-5-methylthiophen-3-yl](4-methoxyphenyl)methyl}piperidine-4-carboxylate

SMILES

CCOC(C(CC1)CCN1C(c1c(NC(c2ccco2)=O)sc(C)c1)c(cc1)ccc1OC)=O

InChI

InChI=1S/C26H30N2O5S/c1-4-32-26(30)19-11-13-28(14-12-19)23(18-7-9-20(31-3)10-8-18)21-16-17(2)34-25(21)27-24(29)22-6-5-15-33-22/h5-10,15-16,19,23H,4,11-14H2,1-3H3,(H,27,29)/t23-/m1/s1

InChI Key

KPKPXKGUPFBWMG-HSZRJFAPSA-N

MDL Number (MFCD)

MFCD09540311

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.6

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.871

Distribution Coefficient, logD

3.392

Water Solubility, LogSw

-4.53

Polar Surface Area

62.753

Acid Dissociation Constant (pKa)

9.90

Base Dissociation Constant (pKb)

8.86

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.50

D411-0374 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Nervous system
Targets:
  • Others

References: we are preparing a list of scientific research reports with D411-0374 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D411-0374?
Check Price and Availability of D411-0374, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D411-0374 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D411-0374
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D411-0374
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D411-0374 available by request