D419-2269 Screening compound: N-(4,6-diphenylpyrimidin-2-yl)-2,2-dimethylpropanamide

D419-2269 Screening compound: N-(4,6-diphenylpyrimidin-2-yl)-2,2-dimethylpropanamide
D419-2269 Screening compound: N-(4,6-diphenylpyrimidin-2-yl)-2,2-dimethylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D419-2269
N-(4,6-diphenylpyrimidin-2-yl)-2,2-dimethylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D419-2269

Molecular Formula

C21H21N3O (C21 H21 N3 O)

Compound Name

N-(4,6-diphenylpyrimidin-2-yl)-2,2-dimethylpropanamide

IUPAC name

N-(46-diphenylpyrimidin-2-yl)-22-dimethylpropanamide

SMILES

CC(C)(C)C(Nc1nc(-c2ccccc2)cc(-c2ccccc2)n1)=O

InChI

InChI=1S/C21H21N3O/c1-21(2,3)19(25)24-20-22-17(15-10-6-4-7-11-15)14-18(23-20)16-12-8-5-9-13-16/h4-14H,1-3H3,(H,22,23,24,25)

InChI Key

NXDIUBGJWKDMMT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14827875

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

331.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.432

Distribution Coefficient, logD

5.432

Water Solubility, LogSw

-5.43

Polar Surface Area

42.763

Acid Dissociation Constant (pKa)

11.45

Base Dissociation Constant (pKb)

1.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

D419-2269 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

Human GPCR Annotated Library (5539 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Targeted Diversity Library (40567 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D419-2269 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D419-2269?
Check Price and Availability of D419-2269, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D419-2269 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D419-2269
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D419-2269
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D419-2269 available by request