D419-2579 Screening compound: N-[4,6-bis(4-methoxyphenyl)pyrimidin-2-yl]benzenesulfonamide

D419-2579 Screening compound: N-[4,6-bis(4-methoxyphenyl)pyrimidin-2-yl]benzenesulfonamide
D419-2579 Screening compound: N-[4,6-bis(4-methoxyphenyl)pyrimidin-2-yl]benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D419-2579
N-[4,6-bis(4-methoxyphenyl)pyrimidin-2-yl]benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D419-2579

Molecular Formula

C24H21N3O4S (C24 H21 N3 O4 S)

Compound Name

N-[4,6-bis(4-methoxyphenyl)pyrimidin-2-yl]benzenesulfonamide

IUPAC name

N-[46-bis(4-methoxyphenyl)pyrimidin-2-yl]benzenesulfonamide

SMILES

COc(cc1)ccc1-c1nc(NS(c2ccccc2)(=O)=O)nc(-c(cc2)ccc2OC)c1

InChI

InChI=1S/C24H21N3O4S/c1-30-19-12-8-17(9-13-19)22-16-23(18-10-14-20(31-2)15-11-18)26-24(25-22)27-32(28,29)21-6-4-3-5-7-21/h3-16H,1-2H3,(H,25,26,27)

InChI Key

VFVKUJKHCYSNMV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14827962

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.524

Distribution Coefficient, logD

5.435

Water Solubility, LogSw

-5.63

Polar Surface Area

75.138

Acid Dissociation Constant (pKa)

8.05

Base Dissociation Constant (pKb)

-1.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

D419-2579 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D419-2579 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D419-2579?
Check Price and Availability of D419-2579, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D419-2579 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D419-2579
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D419-2579
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D419-2579 available by request