D420-2777 Screening compound: 2-(4-methylpiperazin-1-yl)-3-(5-propyl-1,2,4-oxadiazol-3-yl)quinoline

D420-2777 Screening compound: 2-(4-methylpiperazin-1-yl)-3-(5-propyl-1,2,4-oxadiazol-3-yl)quinoline
D420-2777 Screening compound: 2-(4-methylpiperazin-1-yl)-3-(5-propyl-1,2,4-oxadiazol-3-yl)quinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound D420-2777
2-(4-methylpiperazin-1-yl)-3-(5-propyl-1,2,4-oxadiazol-3-yl)quinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D420-2777

Molecular Formula

C19H23N5O (C19 H23 N5 O)

Compound Name

2-(4-methylpiperazin-1-yl)-3-(5-propyl-1,2,4-oxadiazol-3-yl)quinoline

IUPAC name

2-(4-methylpiperazin-1-yl)-3-(5-propyl-124-oxadiazol-3-yl)quinoline

SMILES

CCCc1nc(-c2cc3ccccc3nc2N2CCN(C)CC2)no1

InChI

InChI=1S/C19H23N5O/c1-3-6-17-21-18(22-25-17)15-13-14-7-4-5-8-16(14)20-19(15)24-11-9-23(2)10-12-24/h4-5,7-8,13H,3,6,9-12H2,1-2H3

InChI Key

AEKPUSNCRRXZPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27584928

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

337.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.211

Distribution Coefficient, logD

3.392

Water Solubility, LogSw

-4.34

Polar Surface Area

46.774

Acid Dissociation Constant (pKa)

23.43

Base Dissociation Constant (pKb)

8.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

D420-2777 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Ion Channels
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with D420-2777 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D420-2777?
Check Price and Availability of D420-2777, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D420-2777 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D420-2777
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D420-2777
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D420-2777 available by request