D420-3952 Screening compound: 2-(4-cyclopropanecarbonylpiperazin-1-yl)-6-methyl-3-(5-phenyl-1,2,4-oxadiazol-3-yl)quinoline

D420-3952 Screening compound: 2-(4-cyclopropanecarbonylpiperazin-1-yl)-6-methyl-3-(5-phenyl-1,2,4-oxadiazol-3-yl)quinoline
D420-3952 Screening compound: 2-(4-cyclopropanecarbonylpiperazin-1-yl)-6-methyl-3-(5-phenyl-1,2,4-oxadiazol-3-yl)quinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound D420-3952
2-(4-cyclopropanecarbonylpiperazin-1-yl)-6-methyl-3-(5-phenyl-1,2,4-oxadiazol-3-yl)quinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D420-3952

Molecular Formula

C26H25N5O2 (C26 H25 N5 O2)

Compound Name

2-(4-cyclopropanecarbonylpiperazin-1-yl)-6-methyl-3-(5-phenyl-1,2,4-oxadiazol-3-yl)quinoline

IUPAC name

2-(4-cyclopropanecarbonylpiperazin-1-yl)-6-methyl-3-(5-phenyl-124-oxadiazol-3-yl)quinoline

SMILES

Cc(cc1cc2-c3noc(-c4ccccc4)n3)ccc1nc2N(CC1)CCN1C(C1CC1)=O

InChI

InChI=1S/C26H25N5O2/c1-17-7-10-22-20(15-17)16-21(23-28-25(33-29-23)18-5-3-2-4-6-18)24(27-22)30-11-13-31(14-12-30)26(32)19-8-9-19/h2-7,10,15-16,19H,8-9,11-14H2,1H3

InChI Key

USNMBLZCGZEXFQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14827974

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.680

Distribution Coefficient, logD

5.613

Water Solubility, LogSw

-5.85

Polar Surface Area

60.340

Acid Dissociation Constant (pKa)

22.91

Base Dissociation Constant (pKb)

6.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.80

D420-3952 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D420-3952 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D420-3952?
Check Price and Availability of D420-3952, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D420-3952 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D420-3952
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D420-3952
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D420-3952 available by request