D420-4914 Screening compound: 3-[3-(2-hydroxy-7-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-1-(morpholin-4-yl)propan-1-one

D420-4914 Screening compound: 3-[3-(2-hydroxy-7-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-1-(morpholin-4-yl)propan-1-one
D420-4914 Screening compound: 3-[3-(2-hydroxy-7-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-1-(morpholin-4-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D420-4914
3-[3-(2-hydroxy-7-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-1-(morpholin-4-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D420-4914

Molecular Formula

C19H20N4O4 (C19 H20 N4 O4)

Compound Name

3-[3-(2-hydroxy-7-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-1-(morpholin-4-yl)propan-1-one

IUPAC name

3-[3-(2-hydroxy-7-methylquinolin-3-yl)-124-oxadiazol-5-yl]-1-(morpholin-4-yl)propan-1-one

SMILES

Cc1ccc(cc(-c2noc(CCC(N3CCOCC3)=O)n2)c(O)n2)c2c1

InChI

InChI=1S/C19H20N4O4/c1-12-2-3-13-11-14(19(25)20-15(13)10-12)18-21-16(27-22-18)4-5-17(24)23-6-8-26-9-7-23/h2-3,10-11H,4-9H2,1H3,(H,20,25)

InChI Key

PTIJQFVKJZQJSQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14827981

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.983

Distribution Coefficient, logD

1.513

Water Solubility, LogSw

-2.66

Polar Surface Area

80.902

Acid Dissociation Constant (pKa)

7.11

Base Dissociation Constant (pKb)

2.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

D420-4914 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D420-4914 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D420-4914?
Check Price and Availability of D420-4914, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D420-4914 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D420-4914
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D420-4914
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D420-4914 available by request