D420-6469 Screening compound: 4-[3-(2-hydroxy-6-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]-N-methylbutanamide

D420-6469 Screening compound: 4-[3-(2-hydroxy-6-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]-N-methylbutanamide
D420-6469 Screening compound: 4-[3-(2-hydroxy-6-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]-N-methylbutanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D420-6469
4-[3-(2-hydroxy-6-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]-N-methylbutanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D420-6469

Molecular Formula

C25H26N4O4 (C25 H26 N4 O4)

Compound Name

4-[3-(2-hydroxy-6-methylquinolin-3-yl)-1,2,4-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]-N-methylbutanamide

IUPAC name

4-[3-(2-hydroxy-6-methylquinolin-3-yl)-124-oxadiazol-5-yl]-N-[(4-methoxyphenyl)methyl]-N-methylbutanamide

SMILES

Cc(cc1cc2-c3noc(CCCC(N(C)Cc(cc4)ccc4OC)=O)n3)ccc1nc2O

InChI

InChI=1S/C25H26N4O4/c1-16-7-12-21-18(13-16)14-20(25(31)26-21)24-27-22(33-28-24)5-4-6-23(30)29(2)15-17-8-10-19(32-3)11-9-17/h7-14H,4-6,15H2,1-3H3,(H,26,31)

InChI Key

BGYZVNNELYAVJE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14828053

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.515

Distribution Coefficient, logD

3.902

Water Solubility, LogSw

-4.46

Polar Surface Area

80.039

Acid Dissociation Constant (pKa)

6.91

Base Dissociation Constant (pKb)

3.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

D420-6469 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with D420-6469 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D420-6469?
Check Price and Availability of D420-6469, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D420-6469 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D420-6469
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D420-6469
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D420-6469 available by request