D424-0008 Screening compound: 2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-1-(1H-indol-3-yl)ethan-1-ol

D424-0008 Screening compound: 2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-1-(1H-indol-3-yl)ethan-1-ol
D424-0008 Screening compound: 2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-1-(1H-indol-3-yl)ethan-1-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound D424-0008
2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-1-(1H-indol-3-yl)ethan-1-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D424-0008

Molecular Formula

C22H27N3O (C22 H27 N3 O)

Compound Name

2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-1-(1H-indol-3-yl)ethan-1-ol

IUPAC name

2-[4-(23-dimethylphenyl)piperazin-1-yl]-1-(1H-indol-3-yl)ethan-1-ol

SMILES

Cc1cccc(N2CCN(CC(c3c[nH]c4c3cccc4)O)CC2)c1C

InChI

InChI=1S/C22H27N3O/c1-16-6-5-9-21(17(16)2)25-12-10-24(11-13-25)15-22(26)19-14-23-20-8-4-3-7-18(19)20/h3-9,14,22-23,26H,10-13,15H2,1-2H3/t22-/m0/s1

InChI Key

CXYDHYZSZVSNFY-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD02234703

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.48

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.002

Distribution Coefficient, logD

3.871

Water Solubility, LogSw

-4.03

Polar Surface Area

32.953

Acid Dissociation Constant (pKa)

14.15

Base Dissociation Constant (pKb)

6.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.40

D424-0008 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with D424-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D424-0008?
Check Price and Availability of D424-0008, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D424-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D424-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D424-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D424-0008 available by request