D430-0202 Screening compound: 4-(2-methyl-6-{4-[2-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-4-yl)morpholine

D430-0202 Screening compound: 4-(2-methyl-6-{4-[2-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-4-yl)morpholine
D430-0202 Screening compound: 4-(2-methyl-6-{4-[2-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-4-yl)morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound D430-0202
4-(2-methyl-6-{4-[2-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-4-yl)morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D430-0202

Molecular Formula

C21H24F3N5O2 (C21 H24 F3 N5 O2)

Compound Name

4-(2-methyl-6-{4-[2-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-4-yl)morpholine

IUPAC name

4-(2-methyl-6-{4-[2-(trifluoromethyl)benzoyl]piperazin-1-yl}pyrimidin-4-yl)morpholine

SMILES

Cc1nc(N2CCOCC2)cc(N(CC2)CCN2C(c2c(C(F)(F)F)cccc2)=O)n1

InChI

InChI=1S/C21H24F3N5O2/c1-15-25-18(14-19(26-15)28-10-12-31-13-11-28)27-6-8-29(9-7-27)20(30)16-4-2-3-5-17(16)21(22,23)24/h2-5,14H,6-13H2,1H3

InChI Key

ABODGXRJYFSGFX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14828368

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.253

Distribution Coefficient, logD

3.227

Water Solubility, LogSw

-3.47

Polar Surface Area

48.619

Acid Dissociation Constant (pKa)

23.11

Base Dissociation Constant (pKb)

6.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

D430-0202 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D430-0202 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D430-0202?
Check Price and Availability of D430-0202, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D430-0202 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D430-0202
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D430-0202
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D430-0202 available by request