D430-1038 Screening compound: N,N,2-trimethyl-6-(4-{[5-(2-methyl-1,3-thiazol-4-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyrimidin-4-amine

D430-1038 Screening compound: N,N,2-trimethyl-6-(4-{[5-(2-methyl-1,3-thiazol-4-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyrimidin-4-amine
D430-1038 Screening compound: N,N,2-trimethyl-6-(4-{[5-(2-methyl-1,3-thiazol-4-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D430-1038
N,N,2-trimethyl-6-(4-{[5-(2-methyl-1,3-thiazol-4-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D430-1038

Molecular Formula

C19H24N6O2S3 (C19 H24 N6 O2 S3)

Compound Name

N,N,2-trimethyl-6-(4-{[5-(2-methyl-1,3-thiazol-4-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyrimidin-4-amine

IUPAC name

NN2-trimethyl-6-(4-{[5-(2-methyl-13-thiazol-4-yl)thiophen-2-yl]sulfonyl}piperazin-1-yl)pyrimidin-4-amine

SMILES

Cc1nc(-c(s2)ccc2S(N(CC2)CCN2c2nc(C)nc(N(C)C)c2)(=O)=O)cs1

InChI

InChI=1S/C19H24N6O2S3/c1-13-20-17(23(3)4)11-18(21-13)24-7-9-25(10-8-24)30(26,27)19-6-5-16(29-19)15-12-28-14(2)22-15/h5-6,11-12H,7-10H2,1-4H3

InChI Key

QUPRVOKVLYLPGZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27585470

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.64

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.047

Distribution Coefficient, logD

2.691

Water Solubility, LogSw

-4.06

Polar Surface Area

65.684

Acid Dissociation Constant (pKa)

23.11

Base Dissociation Constant (pKb)

8.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

D430-1038 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with D430-1038 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D430-1038?
Check Price and Availability of D430-1038, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D430-1038 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D430-1038
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D430-1038
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D430-1038 available by request