D430-2327 Screening compound: 3-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-1-(4-{[2-METHYL-6-(PYRROLIDIN-1-YL)PYRIMIDIN-4-YL]AMINO}PHENYL)UREA

D430-2327 Screening compound: 3-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-1-(4-{[2-METHYL-6-(PYRROLIDIN-1-YL)PYRIMIDIN-4-YL]AMINO}PHENYL)UREA
D430-2327 Screening compound: 3-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-1-(4-{[2-METHYL-6-(PYRROLIDIN-1-YL)PYRIMIDIN-4-YL]AMINO}PHENYL)UREA alternative view

Chemical Structure Depiction of ChemDiv screening compound D430-2327
3-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-1-(4-{[2-METHYL-6-(PYRROLIDIN-1-YL)PYRIMIDIN-4-YL]AMINO}PHENYL)UREA

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D430-2327

Molecular Formula

C24H26N6O3 (C24 H26 N6 O3)

Compound Name

3-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-1-(4-{[2-METHYL-6-(PYRROLIDIN-1-YL)PYRIMIDIN-4-YL]AMINO}PHENYL)UREA

IUPAC name

n/a

SMILES

Cc1nc(N2CCCC2)cc(Nc(cc2)ccc2NC(Nc(cc2)cc3c2OCCO3)=O)n1

InChI

InChI=1S/C24H26N6O3/c1-16-25-22(15-23(26-16)30-10-2-3-11-30)27-17-4-6-18(7-5-17)28-24(31)29-19-8-9-20-21(14-19)33-13-12-32-20/h4-9,14-15H,2-3,10-13H2,1H3,(H,25,26,27)(H2,28,29,31)

InChI Key

JYRPMGNHPSPKNV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27585643

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.232

Distribution Coefficient, logD

3.948

Water Solubility, LogSw

-4.21

Polar Surface Area

79.310

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

7.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

D430-2327 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Targeted Diversity Library (40567 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D430-2327 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D430-2327?
Check Price and Availability of D430-2327, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D430-2327 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D430-2327
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D430-2327
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D430-2327 available by request