D430-2381 Screening compound: N-(5-chloro-2-methylphenyl)-4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazine-1-carboxamide

D430-2381 Screening compound: N-(5-chloro-2-methylphenyl)-4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazine-1-carboxamide
D430-2381 Screening compound: N-(5-chloro-2-methylphenyl)-4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D430-2381
N-(5-chloro-2-methylphenyl)-4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D430-2381

Molecular Formula

C24H27ClN6O (C24 H27 ClN6 O)

Compound Name

N-(5-chloro-2-methylphenyl)-4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazine-1-carboxamide

IUPAC name

N-(5-chloro-2-methylphenyl)-4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazine-1-carboxamide

SMILES

Cc(cc1)ccc1Nc1cc(N(CC2)CCN2C(Nc2c(C)ccc(Cl)c2)=O)nc(C)n1

InChI

InChI=1S/C24H27ClN6O/c1-16-4-8-20(9-5-16)28-22-15-23(27-18(3)26-22)30-10-12-31(13-11-30)24(32)29-21-14-19(25)7-6-17(21)2/h4-9,14-15H,10-13H2,1-3H3,(H,29,32)(H,26,27,28)

InChI Key

ZBVDXXLIKUSLPC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27585661

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.97

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.641

Distribution Coefficient, logD

5.125

Water Solubility, LogSw

-5.88

Polar Surface Area

55.397

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

7.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

D430-2381 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D430-2381 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D430-2381?
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What is the minimum amount of D430-2381 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D430-2381
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D430-2381
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D430-2381 available by request