D432-0390 Screening compound: 2-{[5-bromo-2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3-methyl-3,4-dihydroquinazolin-4-one

D432-0390 Screening compound: 2-{[5-bromo-2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3-methyl-3,4-dihydroquinazolin-4-one
D432-0390 Screening compound: 2-{[5-bromo-2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3-methyl-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D432-0390
2-{[5-bromo-2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3-methyl-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D432-0390

Molecular Formula

C21H20BrN3O2 (C21 H20 BrN3 O2)

Compound Name

2-{[5-bromo-2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3-methyl-3,4-dihydroquinazolin-4-one

IUPAC name

2-{[5-bromo-2-oxo-1-(propan-2-yl)-23-dihydro-1H-indol-3-yl]methyl}-3-methyl-34-dihydroquinazolin-4-one

SMILES

CC(C)N(C(C1CC(N2C)=Nc(cccc3)c3C2=O)=O)c(cc2)c1cc2Br

InChI

InChI=1S/C21H20BrN3O2/c1-12(2)25-18-9-8-13(22)10-15(18)16(21(25)27)11-19-23-17-7-5-4-6-14(17)20(26)24(19)3/h4-10,12,16H,11H2,1-3H3/t16-/m0/s1

InChI Key

PYZDPEZMRVERAK-INIZCTEOSA-N

MDL Number (MFCD)

MFCD14828765

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.31

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.046

Distribution Coefficient, logD

3.046

Water Solubility, LogSw

-3.59

Polar Surface Area

40.704

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

3.39

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.60

D432-0390 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D432-0390 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D432-0390?
Check Price and Availability of D432-0390, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D432-0390 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D432-0390
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D432-0390
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D432-0390 available by request