D433-0421 Screening compound: N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-3,4,5-trimethoxy-N-(2-methoxyphenyl)benzamide

D433-0421 Screening compound: N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-3,4,5-trimethoxy-N-(2-methoxyphenyl)benzamide
D433-0421 Screening compound: N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-3,4,5-trimethoxy-N-(2-methoxyphenyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D433-0421
N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-3,4,5-trimethoxy-N-(2-methoxyphenyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D433-0421

Molecular Formula

C25H27N5O5 (C25 H27 N5 O5)

Compound Name

N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-3,4,5-trimethoxy-N-(2-methoxyphenyl)benzamide

IUPAC name

N-({57-dimethyl-[124]triazolo[15-a]pyrimidin-2-yl}methyl)-345-trimethoxy-N-(2-methoxyphenyl)benzamide

SMILES

Cc1cc(C)nc2nc(CN(C(c(cc3OC)cc(OC)c3OC)=O)c(cccc3)c3OC)nn12

InChI

InChI=1S/C25H27N5O5/c1-15-11-16(2)30-25(26-15)27-22(28-30)14-29(18-9-7-8-10-19(18)32-3)24(31)17-12-20(33-4)23(35-6)21(13-17)34-5/h7-13H,14H2,1-6H3

InChI Key

GZRGQNJGJUUIRU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27585836

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.436

Distribution Coefficient, logD

2.436

Water Solubility, LogSw

-2.84

Polar Surface Area

77.479

Acid Dissociation Constant (pKa)

25.44

Base Dissociation Constant (pKb)

1.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

D433-0421 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with D433-0421 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D433-0421?
Check Price and Availability of D433-0421, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D433-0421 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D433-0421
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D433-0421
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D433-0421 available by request