D433-0452 Screening compound: N-(2-chlorophenyl)-N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-2-methylpropanamide

D433-0452 Screening compound: N-(2-chlorophenyl)-N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-2-methylpropanamide
D433-0452 Screening compound: N-(2-chlorophenyl)-N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D433-0452
N-(2-chlorophenyl)-N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D433-0452

Molecular Formula

C18H20ClN5O (C18 H20 ClN5 O)

Compound Name

N-(2-chlorophenyl)-N-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}methyl)-2-methylpropanamide

IUPAC name

N-(2-chlorophenyl)-N-({57-dimethyl-[124]triazolo[15-a]pyrimidin-2-yl}methyl)-2-methylpropanamide

SMILES

CC(C)C(N(Cc1nn2c(C)cc(C)nc2n1)c(cccc1)c1Cl)=O

InChI

InChI=1S/C18H20ClN5O/c1-11(2)17(25)23(15-8-6-5-7-14(15)19)10-16-21-18-20-12(3)9-13(4)24(18)22-16/h5-9,11H,10H2,1-4H3

InChI Key

HIXCAOLZUQZORG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27585848

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.84

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.812

Distribution Coefficient, logD

2.812

Water Solubility, LogSw

-3.33

Polar Surface Area

47.142

Acid Dissociation Constant (pKa)

20.52

Base Dissociation Constant (pKb)

1.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

D433-0452 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D433-0452 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D433-0452?
Check Price and Availability of D433-0452, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D433-0452 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D433-0452
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D433-0452
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D433-0452 available by request