D437-0103 Screening compound: N-[4-(4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-1,3-thiazol-2-yl]-2,2-diphenylacetamide

D437-0103 Screening compound: N-[4-(4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-1,3-thiazol-2-yl]-2,2-diphenylacetamide
D437-0103 Screening compound: N-[4-(4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-1,3-thiazol-2-yl]-2,2-diphenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D437-0103
N-[4-(4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-1,3-thiazol-2-yl]-2,2-diphenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D437-0103

Molecular Formula

C26H21N3O3S (C26 H21 N3 O3 S)

Compound Name

N-[4-(4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-1,3-thiazol-2-yl]-2,2-diphenylacetamide

IUPAC name

N-[4-(4-methyl-3-oxo-34-dihydro-2H-14-benzoxazin-6-yl)-13-thiazol-2-yl]-22-diphenylacetamide

SMILES

CN1c(cc(cc2)-c3csc(NC(C(c4ccccc4)c4ccccc4)=O)n3)c2OCC1=O

InChI

InChI=1S/C26H21N3O3S/c1-29-21-14-19(12-13-22(21)32-15-23(29)30)20-16-33-26(27-20)28-25(31)24(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-14,16,24H,15H2,1H3,(H,27,28,31)

InChI Key

BKKNCKUFLOPKGH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10088306

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.964

Distribution Coefficient, logD

4.964

Water Solubility, LogSw

-4.69

Polar Surface Area

56.700

Acid Dissociation Constant (pKa)

10.25

Base Dissociation Constant (pKb)

-1.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

D437-0103 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D437-0103 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D437-0103?
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What is the minimum amount of D437-0103 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D437-0103
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D437-0103
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D437-0103 available by request