D455-1263 Screening compound: 6-(3-methoxyphenyl)-1,1-dioxo-N~5~-(2-pyridyl)-2,3-dihydro-1H-1lambda~6~-imidazo[2,1-b][1,3]thiazole-5-carboxamide

D455-1263 Screening compound: 6-(3-methoxyphenyl)-1,1-dioxo-N~5~-(2-pyridyl)-2,3-dihydro-1H-1lambda~6~-imidazo[2,1-b][1,3]thiazole-5-carboxamide
D455-1263 Screening compound: 6-(3-methoxyphenyl)-1,1-dioxo-N~5~-(2-pyridyl)-2,3-dihydro-1H-1lambda~6~-imidazo[2,1-b][1,3]thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D455-1263
6-(3-methoxyphenyl)-1,1-dioxo-N~5~-(2-pyridyl)-2,3-dihydro-1H-1lambda~6~-imidazo[2,1-b][1,3]thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D455-1263

Molecular Formula

C18H16N4O4S (C18 H16 N4 O4 S)

Compound Name

6-(3-methoxyphenyl)-1,1-dioxo-N~5~-(2-pyridyl)-2,3-dihydro-1H-1lambda~6~-imidazo[2,1-b][1,3]thiazole-5-carboxamide

IUPAC name

6-(3-methoxyphenyl)-11-dioxo-N-(pyridin-2-yl)-2H3H-1lambda6-imidazo[21-b][13]thiazole-5-carboxamide

SMILES

COc1cccc(-c2c(C(Nc3ncccc3)=O)n(CCS3(=O)=O)c3n2)c1

InChI

InChI=1S/C18H16N4O4S/c1-26-13-6-4-5-12(11-13)15-16(17(23)20-14-7-2-3-8-19-14)22-9-10-27(24,25)18(22)21-15/h2-8,11H,9-10H2,1H3,(H,19,20,23)

InChI Key

DSPQHIVNFFPOAJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27587421

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.42

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.335

Distribution Coefficient, logD

2.329

Water Solubility, LogSw

-3.06

Polar Surface Area

81.766

Acid Dissociation Constant (pKa)

9.26

Base Dissociation Constant (pKb)

3.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

D455-1263 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Proteases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D455-1263 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D455-1263?
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What is the minimum amount of D455-1263 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D455-1263
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D455-1263
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D455-1263 available by request