D458-1257 Screening compound: N-(3-chloro-4-methylphenyl)-2-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]acetamide

D458-1257 Screening compound: N-(3-chloro-4-methylphenyl)-2-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]acetamide
D458-1257 Screening compound: N-(3-chloro-4-methylphenyl)-2-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D458-1257
N-(3-chloro-4-methylphenyl)-2-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D458-1257

Molecular Formula

C19H21ClN4OS (C19 H21 ClN4 OS)

Compound Name

N-(3-chloro-4-methylphenyl)-2-[1-(4,5-dimethyl-1,3-thiazol-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]acetamide

IUPAC name

N-(3-chloro-4-methylphenyl)-2-[1-(45-dimethyl-13-thiazol-2-yl)-35-dimethyl-1H-pyrazol-4-yl]acetamide

SMILES

Cc1c(CC(Nc2cc(Cl)c(C)cc2)=O)c(C)nn1-c1nc(C)c(C)s1

InChI

InChI=1S/C19H21ClN4OS/c1-10-6-7-15(8-17(10)20)22-18(25)9-16-12(3)23-24(13(16)4)19-21-11(2)14(5)26-19/h6-8H,9H2,1-5H3,(H,22,25)

InChI Key

ONLBFUWUXGMGMV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27588074

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.92

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.804

Distribution Coefficient, logD

4.523

Water Solubility, LogSw

-4.86

Polar Surface Area

47.931

Acid Dissociation Constant (pKa)

10.07

Base Dissociation Constant (pKb)

7.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

D458-1257 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with D458-1257 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D458-1257?
Check Price and Availability of D458-1257, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D458-1257 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D458-1257
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D458-1257
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D458-1257 available by request