D463-0165 Screening compound: 3-(4-fluorophenyl)-5-methyl-N-[(pyridin-3-yl)methyl]-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine

D463-0165 Screening compound: 3-(4-fluorophenyl)-5-methyl-N-[(pyridin-3-yl)methyl]-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine
D463-0165 Screening compound: 3-(4-fluorophenyl)-5-methyl-N-[(pyridin-3-yl)methyl]-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D463-0165
3-(4-fluorophenyl)-5-methyl-N-[(pyridin-3-yl)methyl]-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D463-0165

Molecular Formula

C20H15F4N5 (C20 H15 F4 N5)

Compound Name

3-(4-fluorophenyl)-5-methyl-N-[(pyridin-3-yl)methyl]-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine

IUPAC name

3-(4-fluorophenyl)-5-methyl-N-[(pyridin-3-yl)methyl]-2-(trifluoromethyl)pyrazolo[15-a]pyrimidin-7-amine

SMILES

Cc(cc(NCc1cnccc1)n1nc2C(F)(F)F)nc1c2-c(cc1)ccc1F

InChI

InChI=1S/C20H15F4N5/c1-12-9-16(26-11-13-3-2-8-25-10-13)29-19(27-12)17(18(28-29)20(22,23)24)14-4-6-15(21)7-5-14/h2-10,26H,11H2,1H3

InChI Key

HULIGLNYFHRQCJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18180908

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.37

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.571

Distribution Coefficient, logD

3.537

Water Solubility, LogSw

-3.53

Polar Surface Area

40.614

Acid Dissociation Constant (pKa)

17.59

Base Dissociation Constant (pKb)

6.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

D463-0165 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D463-0165 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D463-0165?
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What is the minimum amount of D463-0165 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D463-0165
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D463-0165
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D463-0165 available by request