D464-0368 Screening compound: 1-[4-(pyridin-2-yl)piperazin-1-yl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]ethan-1-one

D464-0368 Screening compound: 1-[4-(pyridin-2-yl)piperazin-1-yl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]ethan-1-one
D464-0368 Screening compound: 1-[4-(pyridin-2-yl)piperazin-1-yl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D464-0368
1-[4-(pyridin-2-yl)piperazin-1-yl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D464-0368

Molecular Formula

C18H18N4OS2 (C18 H18 N4 OS2)

Compound Name

1-[4-(pyridin-2-yl)piperazin-1-yl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]ethan-1-one

IUPAC name

1-[4-(pyridin-2-yl)piperazin-1-yl]-2-[4-(thiophen-2-yl)-13-thiazol-5-yl]ethan-1-one

SMILES

O=C(Cc1c(-c2cccs2)ncs1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C18H18N4OS2/c23-17(12-15-18(20-13-25-15)14-4-3-11-24-14)22-9-7-21(8-10-22)16-5-1-2-6-19-16/h1-6,11,13H,7-10,12H2

InChI Key

RXUBXMLDAMCRPN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10088629

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.372

Distribution Coefficient, logD

3.363

Water Solubility, LogSw

-3.44

Polar Surface Area

39.276

Acid Dissociation Constant (pKa)

17.80

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

D464-0368 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with D464-0368 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D464-0368?
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What is the minimum amount of D464-0368 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D464-0368
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D464-0368
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D464-0368 available by request