D471-2767 Screening compound: 3-(2,4-difluorophenyl)-1-[2-({[1-(2-methylpropyl)-7-oxo-1H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]methyl}sulfanyl)phenyl]urea

D471-2767 Screening compound: 3-(2,4-difluorophenyl)-1-[2-({[1-(2-methylpropyl)-7-oxo-1H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]methyl}sulfanyl)phenyl]urea
D471-2767 Screening compound: 3-(2,4-difluorophenyl)-1-[2-({[1-(2-methylpropyl)-7-oxo-1H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]methyl}sulfanyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound D471-2767
3-(2,4-difluorophenyl)-1-[2-({[1-(2-methylpropyl)-7-oxo-1H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]methyl}sulfanyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D471-2767

Molecular Formula

C23H22F2N6O2S (C23 H22 F2 N6 O2 S)

Compound Name

3-(2,4-difluorophenyl)-1-[2-({[1-(2-methylpropyl)-7-oxo-1H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]methyl}sulfanyl)phenyl]urea

IUPAC name

3-(24-difluorophenyl)-1-[2-({[1-(2-methylpropyl)-7-oxo-1H7H-[124]triazolo[15-a]pyrimidin-5-yl]methyl}sulfanyl)phenyl]urea

SMILES

CC(C)CN(C=NC1=NC(CSc(cccc2)c2NC(Nc(ccc(F)c2)c2F)=O)=C2)N1C2=O

InChI

InChI=1S/C23H22F2N6O2S/c1-14(2)11-30-13-26-22-27-16(10-21(32)31(22)30)12-34-20-6-4-3-5-19(20)29-23(33)28-18-8-7-15(24)9-17(18)25/h3-10,13-14H,11-12H2,1-2H3,(H2,28,29,33)

InChI Key

LVUGXBRYRXSZTE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27588276

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.455

Distribution Coefficient, logD

3.451

Water Solubility, LogSw

-3.88

Polar Surface Area

71.425

Acid Dissociation Constant (pKa)

10.55

Base Dissociation Constant (pKb)

5.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

D471-2767 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with D471-2767 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D471-2767?
Check Price and Availability of D471-2767, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D471-2767 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D471-2767
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D471-2767
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D471-2767 available by request