D473-1940 Screening compound: 1-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-N~3~-(2-furylmethyl)-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide

D473-1940 Screening compound: 1-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-N~3~-(2-furylmethyl)-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide
D473-1940 Screening compound: 1-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-N~3~-(2-furylmethyl)-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D473-1940
1-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-N~3~-(2-furylmethyl)-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D473-1940

Molecular Formula

C20H21N3O5S (C20 H21 N3 O5 S)

Compound Name

1-(1,1-dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)-N~3~-(2-furylmethyl)-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide

IUPAC name

1-(11-dioxo-1lambda6-thiolan-3-yl)-N-[(furan-2-yl)methyl]-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide

SMILES

COc(cc1)ccc1-c1cc(C(NCc2ccco2)=O)nn1C(CC1)CS1(=O)=O

InChI

InChI=1S/C20H21N3O5S/c1-27-16-6-4-14(5-7-16)19-11-18(20(24)21-12-17-3-2-9-28-17)22-23(19)15-8-10-29(25,26)13-15/h2-7,9,11,15H,8,10,12-13H2,1H3,(H,21,24)/t15-/m1/s1

InChI Key

ARXXIMPXMTUALQ-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD10043148

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.240

Distribution Coefficient, logD

2.240

Water Solubility, LogSw

-2.88

Polar Surface Area

81.038

Acid Dissociation Constant (pKa)

12.90

Base Dissociation Constant (pKb)

-1.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.00

D473-1940 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D473-1940 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D473-1940?
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What is the minimum amount of D473-1940 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D473-1940
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D473-1940
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D473-1940 available by request